Tranexamic acid and mefenamic acid tablets are a highly effective combination therapy for reducing heavy menstrual bleeding (HMB). These tablets work by targeting different mechanisms involved in excessive menstrual blood loss.
Tranexamic acid inhibits the breakdown of fibrin, a protein involved in blood clot formation. By reducing fibrinolysis, it helps to stabilize blood clots and reduce bleeding.
Mefenamic acid is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits COX-2, an enzyme responsible for prostaglandin production. Prostaglandins are known to promote uterine contractions and blood vessel dilation, contributing to heavy menstrual bleeding.
Clinical studies have consistently demonstrated the efficacy of tranexamic acid and mefenamic acid tablets in reducing HMB.
Parameter | Effect | Reference |
---|---|---|
Reduction in menstrual blood loss | 50-80% | British Journal of Obstetrics and Gynaecology |
Improvement in hemoglobin levels | 1-2 g/dL | American Journal of Obstetrics and Gynecology |
Tolerability | Generally well-tolerated | Medicines and Healthcare products Regulatory Agency (MHRA) |
If you suffer from heavy menstrual bleeding, talk to your healthcare provider about the effectiveness of tranexamic acid and mefenamic acid tablets. This combination therapy can help you regain control of your menstrual cycle and improve your quality of life.
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